I haven't seen Let Me In, the American adaptation of the Sweedish Vampire film Let the Right One In (which is an interesting film and certainly worth a rental). However, Seitz includes this excellent analysis for one scene which explains why he thinks its the best scene of 2010:
His second favorite scene is from Toy Story 3, and I have to agree. It is a pretty powerful scene and I'm not above admitting that I shed a few tears at this pixar film (and apparently I'm not the only one). In this clip - he explains what makes the climactic scene so powerful (but beware, this contains spoilers).
Each of his top ten films receive their own post, you can read about them and see the clips here.
1. Let Me In
2. Toy Story 3
3. Winter's Bone
4. Dogtooth
5. The Social Network
6. Ne Change Rien
7. Shutter Island
8. Somewhere
9. The Ghost Writer
10. Solitary Man
What I find is really successful about his analysis is how he connects his personal experiential reactions to film with the cinematographic techniques and stylistic choices made by the directors.